Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia
Recurrent deletions of the long arm of chromosome 5 were detected in 23/200 cases of T-cell acute lymphoblastic leukemia.Genomic studies identified two types of deletions: interstitial and terminal.Interstitial 5q deletions, found in five cases, were present in both adults and children with a female predominance (chi-square, P=0.012).Interestingly,